Sepsis is a life-threatening condition caused by infection-induced immune dysregulation, leading to organ dysfunction and high mortality. Although the Sepsis-3 criteria use SOFA-based organ dysfunction as the diagnostic standard, waiting until organ damage occurs may miss the optimal intervention window, contributing to millions of deaths worldwide each year. The concept of pre-sepsis(early sepsis) has emerged as a critical stage after infection onset, where immune […]

The consensus sets evidence-based standards for nationwide blood establishments to standardize blood screening workflows, optimize blood donor management, and strike a balance between blood safety and the rights and interests of blood donors. Furthermore, the consensus identifies the following limitations of the Guidelines for Re-entry of Blood Donors with Reactive Screening Results: “It only addresses serological test findings, without fully leveraging […]

In recent years, heartbreaking headlines have become familiar: high-performing professionals in the prime of their careers, dedicated gym-goers, even trained marathon runners collapsing from sudden cardiac arrest without warning. By all appearances, they were energetic — often more disciplined about their health than most. These tragedies shatter the “health halo” we take for granted and force a stark medical question upon us: looking healthy is […]

In China, the prevalence of Helicobacter pylori (H. pylori, or Hp) infection is as high as 40%–50%, meaning that nearly one in two people may be infected. H. pylori infection is a major cause of chronic gastritis, peptic ulcers, and gastric cancer, making accurate diagnosis the first step toward effective management. In July 2026, the Helicobacter pylori Study Group of […]

When cancer is mentioned, people often think of genetics, environmental factors or unhealthy lifestyles. However, what may be less known is that approximately 15%-20% of cancer cases worldwide can be attributed to chronic viral infections. Among these pathogens, HBV and HCV are major viral drivers of Hepatocellular Carcinoma (HCC), while HIV-associated immunodeficiency substantially increases the risk of several AIDS-defining and […]